Wilkes University Modeling Antibiotic Resistance Questions Response Hi there,Could you please answer these questions by using the giving data? The equation

Wilkes University Modeling Antibiotic Resistance Questions Response Hi there,Could you please answer these questions by using the giving data? The equations include short answers and 1 page essay. All information provided on the pictures.Thank you Alanazi
Talan
Modeling Antibiotic Resistance
Based on an exercise presented to the Association of Biology Laboratory Education
by Marion and Ralph Preszler, New Mexico State University
1) Your “organism” is your plastic bin. The “bacteria” are a variety of random
household items. Choose four species of “bacteria” to infect your organism with.
??
2) Your instructor will provide your group with an “antibiotic”; another household item
that will be used to pick up and remove the bacteria from your organism.
3) Infect your organism with 25 individual bacteria from each of the four species (a total
of 100 in the organism).
E
new
4) When your
instructor says “GO”, use your antibiotics to remove as many bacteria as
possible from your organism. You will have 15 seconds to do this. Record your results
below and calculate how the population will rebound:
Trial 1
A
B
C
D
Total in
Percent
Species # Left
Left
population # to Add
B/*TOTAL 100 *C
D – B
?
21
27
1
6
11
0 14
14
3
2
3
23
29
6
3
23
O !
4
6
*TOTAL: 79
cotton
Q-tips
O. 27
0-14
0.11
Selley
29
?
5) Repeat the experiment using your new population after recovery and record again
below:
Trial 2
A
B
C
D
E
Total in
Percent new
Species # Left
Left population # to Add
B/*TOTAL 100 * C
D – B
cotton
2 6.03
3.
1
1
MSM
0.017
2
2
Mas
29 0.48 48
3
28
0.46
46
4
18.
*TOTAL: 60
1
19
( Mom
ander
E
6) Repeat twice more and record the results below:
Trial 3
A
B
C
D
Total in
Percent new
Species # Left
Left
population
B/*TOTAL
100 * C
Cotton
O
O
1
0
0
2
O
O
O
0.53
43
3
53
38
4
0.47 47
*TOTAL: 81
1
# to Add
D – B
0 O
0 o
10
9
w
Jellel
Trial 4
A
B
?
1
2
Percent
Species # Left
Left
B/*TOTAL
0
O
O
47
3
0.58
35 0,43
82
7) Reset the experiment to the original population numbers. This time your time period
will be a single 60-second run. Record your results below:
4
*TOTAL:
A
B
?
Species
# Left
Percent
Left
B/*TOTAL
O
1
2
3
O
O
9
5 ?
14.
O
0.64
0.35
4
*TOTAL:
Make a graph with “Trials” on the X-axis and “% left” on the Y-axis. Put a different line
for each of your bacteria on the graph.
Questions:
1) The multiple 15-second trial represents a typical patient who takes antibiotics
repeatedly but never completes the course. The single 60-second trial represents a person
taking the full course of antibiotics one time. Interpret your results in this context.
2)
Explain how the various characteristics of your bacterial species relate to the success
of your antibiotic. Which species was the easiest to remove? The hardest? Given what
you know, suggest a household item that would best represent MRSA (which has
resistance to multiple antibiotics) and explain why.
3) Explain how the characteristics of your “antibiotic” affected your success in
eradicating the various bacteria. Did your antibiotic represent a broad, general antibiotic,
or a very specific one? Elaborate. Suggest a common household item that would
represent a very effective general antibiotic.
4) Create and describe a version of this exercise that would represent the best way to
effectively treat bacterial disease. In other words, describe a way you could most
effectively rid your organism of all of its bacterial infections.
5) Not all bacteria are harmful. Research and then describe how an antibiotic could
negatively affect the “good” bacteria that humans rely on.
6) Choose any antibiotic available today (penicillin and ampicillin are boring). Research
the product and write a short (~ one page) essay. Include:
a) The type of chemical the antibiotic is (including its source)
b) The types of bacteria it is most effective against
c) The cellular mechanism by which it either kills or disarms susceptible bacteria
d) Any known resistances to the antibiotic
**** NOTE: Please go beyond Wikipedia and the like for your research! Cite any
sources
that
you
used. I will randomly check for plagiarism in the essays.

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