Principles of Molecular Biology Protein Annotation Project Assignment exploit knowledge of the fundamental principles of molecular biology to analyze contr

Principles of Molecular Biology Protein Annotation Project Assignment exploit knowledge of the fundamental principles of molecular biology to analyze contributions of DNA and proteins to human physiology and behavior
identify, select, and query the appropriate database to best answer the bioinformatics question at hand, and effectively and accurately interpret the outcome

For the protein annotation project, you will use the protein coded by the gene in the gene annotation project, if it was noncoding gene, choose any protein of interest to annotate. The following tasks must be completed and must provide screenshots

Provide the protein sequence from the provided gene sequence and state protein name, gene name and amino acid length. Include accession ID or protein ID from UniProt, or NCBI
identify the protein function
protein family, conserved domains: name and location by amino acid number
gene ontology (GO): Provide 2 GOs per each one of these sections where available. Sections: Molecular function, Biological process and cellar component. Include GO ID, name, and definition
computational analysis of protein-protein interactions: total number of interactors and at least three names and protein ids of the interactors where available, if there is none, choose 3 other unique features of your protein not on the list

Do not cut and paste your database results to report your findings. Write two to three paragraphs reporting the information you have obtained about this protein. Imagine this is a report you will present to an employer or a group of researchers interested in this protein.

Content

Excellent

Very Good

Good

Fair

Poor

Points

4

3

2

1

0

Protein Identification

correct identification of protein name, gene name, sequence, protein id and amino acid length

correctly identifies at least three of the listed features

correctly identifies at least two of the listed features.

Wrong identification of all the listed features

no answer

Protein Function

All functions

most functions

Some functions

Wrong protein function identification

no answer

Family and Domain information

Correct protein family, conserved domain names, amino acid location

Correctly identifies two of the three required features

Correctly identifies one of the required three features

Wrong identification for all

no answer

Gene ontology information

Have correct six GO terms in three sections including id name and definition

Have correct six Go terms in the three sections but is missing the required description

Have no fewer than three correct GO terms with some description

Have fewer than three correct GO terms

no answer

Protein –protein interactions

Correctly Identifies all the three interactors with protein names and ids

Correctly identifies fewer three interactors but has the names and protein ids

Correctly identifies all the three interactors with missing names and ids

Identifies fewer than three interactors with no names and ids

No answer