Biochemistry Cell and Biology Article pls use the attached template to write the article. 2019 New and Views Assignment Articles Topic 1 Nat Commun. 201

Biochemistry Cell and Biology Article pls use the attached template to write the article.

2019 New and Views Assignment Articles

Topic 1

Nat Commun. 2019 Mar 5;10(1):1050. doi: 10.1038/s41467-019-08982-9.

Loss of a proteostatic checkpoint in intestinal stem cells contributes to age-related epithelial dysfunction.

Topic 2

J Cell Sci. 2016 Mar 1;129(5):994-1002. doi: 10.1242/jcs.176792. Epub 2016 Jan 26.

Appoptosin interacts with mitochondrial outer-membrane fusion proteins and regulates mitochondrial morphology.

Topic 3

Nat Chem Biol. 2017 Dec;13(12):1239-1244. doi: 10.1038/nchembio.2493. Epub 2017 Oct 9.

Stendomycin selectively inhibits TIM23-dependent mitochondrialprotein import.

Topic 4

Mol Cell. 2019 Mar 6. pii: S1097-2765(19)30100-5. doi: 10.1016/j.molcel.2019.02.010. [Epub ahead of print]

Spatiotemporal Control of ULK1 Activation by NDP52 and TBK1 during Selective Autophagy.

Topic 5

Nat Commun. 2016 Nov 24;7:13565. doi: 10.1038/ncomms13565.

The Apaf-1 apoptosome induces formation of caspase-9 homo- and heterodimers with distinct activities.

Topic 6

EMBO J. 2018 Sep 3;37(17). pii: e99238. doi: 10.15252/embj.201899238. Epub 2018 Jul 26.

Mitochondrial inner membrane permeabilisation enables mtDNA release during apoptosis. 2019 New and Views Assignment Articles
Topic 1
Nat Commun. 2019 Mar 5;10(1):1050. doi: 10.1038/s41467-019-08982-9.
Loss of a proteostatic checkpoint in intestinal stem cells contributes to age-related epithelial
dysfunction.
Topic 2
J Cell Sci. 2016 Mar 1;129(5):994-1002. doi: 10.1242/jcs.176792. Epub 2016 Jan 26.
Appoptosin interacts with mitochondrial outer-membrane fusion
proteins and regulates mitochondrial morphology.
Topic 3
Nat Chem Biol. 2017 Dec;13(12):1239-1244. doi: 10.1038/nchembio.2493. Epub 2017 Oct 9.
Stendomycin selectively inhibits TIM23-dependent mitochondrialprotein import.
Topic 4
Mol Cell. 2019 Mar 6. pii: S1097-2765(19)30100-5. doi: 10.1016/j.molcel.2019.02.010. [Epub ahead
of print]
Spatiotemporal Control of ULK1 Activation by NDP52 and TBK1 during Selective Autophagy.
Topic 5
Nat Commun. 2016 Nov 24;7:13565. doi: 10.1038/ncomms13565.
The Apaf-1 apoptosome induces formation of caspase-9 homoand heterodimers with distinct activities.
Topic 6
EMBO J. 2018 Sep 3;37(17). pii: e99238. doi: 10.15252/embj.201899238. Epub 2018 Jul 26.
Mitochondrial inner membrane permeabilisation enables mtDNA release during apoptosis.
NEWS & VIEWS
SUBJECT HERE
Title Here
Type your brief description here. Use no more than two sentences.
YOUR NAME HERE
Follow the following format when
writing your article.
Enter your text in three columns.
Use Times New Roman with 11point font (justified with hyphenation).
Articles should be no longer than
1000 words.
Titles should contain no punctuation
marks or abbreviations.
News and Views articles also carry
a ‘strapline’ of one or two words to
define the general subject area of
the article, and a sentence to summarize the message of the article in
simple language.
The ‘News’ is mentioned in a succinct opening paragraph to attract
the attention of those who are not
experts in the field. This paragraph
should explicitly refer to the paper
under discussion and touch on the
significance of the new work.
References must be between 8 and
12, given superscript numbers and
cited sequentially in the text, as per
Nature style.
References are listed at the end of
the article in the usual Nature style
but without the titles of the citations.
Articles should not read like textbooks – assume your reader has
general biochemical/scientific background but avoid specialized terminology.
Following approval of your planned
article, you should begin the drafting process.
of the topic. This balancing act will
require some thought and careful
writing!
Target your article to someone with
a working knowledge of Biochemistry, Molecular and Cellular Biology
but who is not a specialist in the
particular topic you have chosen (so
someone a bit similar to you).
Even though the focus of a “News
and Views” article is a single paper,
the proportion of the article that is
simply a summary of the paper is
really quite small – only a couple of
paragraphs. The bulk of your article
You will be restricted to using one figure, used to explain the new model
or the background science to the new result. This must be an original
figure that you design and not a simple cut and paste of an existing figure! Place it in the article like this with tight wrapping of the text around
the figure.
Figure 1. The figure should be appropriately labelled and include a detailed
caption.
should be devoted to explaining the
background, the context and the
importance of the results reported.
Nevertheless, the article should focus on the contents of the paper –
and not simply be a general review
Writing a “News and Views” Review Article.
As the major assignment for Advanced Topics in Biochemistry and Cell Biology (BCH3ATB), you will
write a short review article on a topic related to Organelle Biosynthesis or Apoptosis. These topics
will make up a significant component of the lecture content this term. Attending and studying this
lecture material will aid in the composition of your review article and the deep reading required to
compose your review article will benefit your exam preparation on these topics.
Your review article will be written in the style of Nature’s “News and Views”. These articles are
intended for the interested non-specialist to inform them of new scientific advances. They aim to
provide a summary of a paper and an assessment of how it fits into the context of its field.
Therefore, a single paper forms the foundation for a News and Views article. The main findings of
the paper form the “News” but the “Views” are its importance and the implications of its findings.
These “Views” need to be supported using other papers.
Please have a look at some recent News and Views articles (download the PDF versions) to see the
general format and structure:
http://www.nature.com/nature/archive/category.html?code=archive_news_views&year=2015&month=07
You need to find an original research paper conforming to the following guidelines.
•
It must be an original research paper (not a review).
•
Published in 2015-2019.
•
The journal it is published in must be from the following list; Nature (and journals within the
Nature Publishing Group), Science, Proceedings of the National Academy of Sciences (PNAS),
Cell (and Cell Press Journals), EMBO Journal, EMBO Reports, Journal of Cell Biology, Journal
of Cell Science. If you choose an article from outside this list of journals, please provide
additional justification explaining your choice.
•
The paper should not have already had a Commentary or News and Views article published
about its findings. You will need to do a search to confirm this – use PubMed. When you are
looking at abstracts you will notice that Commentary/News and Views articles are often
linked under the heading “Comment in” (see below). If this is the case you definitely must
find another article.
•
The paper should fit under at least one of the following research topics:
Cell Cycle and Mitosis
Mitochondrial Dynamics (Fission, Fusion and/or Distribution)
Mitochondrial Protein Import
Mitophagy
Formation of the Apoptosome
Regulation of the Mitochondrial Apoptotic Pathway
(Notice, that just above the title in the News and Views articles is some highlighted text
(strapline) that denotes the general subject of the paper. The topic you choose from the list
above will be the subject of your review).
After you have chosen the paper on which you are basing your news and view article you will need
to submit the title, subject strapline, a sentence describing the article and a reference for your paper
for approval.
Download the approval form from the LMS and submit this electronically to the LMS anytime before
due date
After approval is given, begin work on your article.
Even though the focus of a “News and Views” article is a single paper, the proportion of the article
that is simply a summary of the paper is really quite small – only a couple of paragraphs. The bulk of
your article should be devoted to explaining the background, the context and the importance of the
results reported. Nevertheless, the article should focus on the contents of the paper – and not
simply be a general review of the topic. This balancing act will require some thought and careful
writing!
Target your article to someone with a working knowledge of Biochemistry, Molecular and Cellular
Biology but who is not a specialist in the particular topic you have chosen (so someone a bit similar
to yourself). A typical “News and Views” article:
•
•
•
•
Starts by providing a brief summary of necessary background information, which a nonspecialist reader would not be likely to know.
Provides information which is not essential to the contents of the paper, but which helps to
set the results in context.
Explains the basis for some conclusions reached by the authors of the paper.
Provides an independent discussion of the questions raised by the results and their possible
implications. Ideally, you will draw your own conclusions, not simply summarise those of
the paper.
Follow the following format when writing your article (please see the template provided)
•
Articles should be no longer than 1000 words.
•
Titles should contain no punctuation marks or abbreviations.
•
News and Views articles also carry a ‘strapline’ of one or two words to define the general
subject area of the article, and a sentence to summarize the message of the article in simple
language.
•
The ‘News’ should be mentioned in a succinct opening paragraph to attract the attention of
those who are not experts in the field. This paragraph should explicitly refer to the paper
under discussion and touch on the significance of the new work.
•
Articles should not read like textbooks – assume your reader has general
biochemical/scientific background but avoid specialized terminology.
•
You will be restricted to using one figure, used to explain the new model or the background
science to the new result. This must be an original figure that you design and not a simple
cut and paste of an existing figure! The figure should be appropriately labelled and include a
detailed caption.
•
References must be between 8 and 12, given superscript numbers and cited sequentially in
the text, as per Nature style. References need to be listed at the end of the article in the
usual Nature style but without the titles of citations.
Both submission and feedback will be done electronically through Turnitin on the LMS.

Purchase answer to see full
attachment